ATTR-CM (transthyretin amyloid cardiomyopathy) is a rare, life-threatening, underrecognized, and underdiagnosed type of amyloidosis that affects the heart
and is associated with heart failure.
Amyloidosis is a group of diseases in which certain proteins change shape, or “misfold,” and can build up in different parts of the body. When these misfolded proteins build up in your heart, it may lead to ATTR-CM.