ATTR-CM (transthyretin amyloid cardiomyopathy) is a serious, underrecognized, and underdiagnosed type of amyloidosis that affects the heart and is associated with heart failure.

Amyloidosis is a group of diseases in which certain proteins change shape, or “misfold,” and can build up in different parts of the body. When these misfolded proteins build up in your heart, it may lead to ATTR-CM.

What is ATTR-CM and how does it affect the body?

See what happens inside the body if you have ATTR-CM.

When should I suspect ATTR-CM?

If you've been diagnosed with heart failure, learn to recognize the signs and symptoms of ATTR-CM. Remember to talk to your doctor about any changes in your health.

How do I know if it’s ATTR-CM?

Only a doctor can diagnose ATTR-CM. If ATTR-CM is suspected, your doctor can perform several tests to help diagnose the disease and to identify whether you or a loved one may be at risk.

How can I prepare to talk with my doctor about ATTR-CM?

Get a personalized discussion guide based on your input. Simply answer 4 questions and you’ll receive a guide to help prepare you for a conversation with your cardiologist about ATTR-CM.


If you have been diagnosed with ATTR-CM, or would like to know more about it, you are not alone. Hear from real patients and caregivers about their journey to diagnosis and living with ATTR-CM.