Your cardiologist may order the following tests to assess how your heart is working and look for signs that may suggest ATTR-CM:
Electrocardiogram or ECG
- Reads electrical signals from your heart through wires or electrical sensing leads attached to the skin with sticker-like patches. ECG findings associated with ATTR-CM include, but are not limited to, an irregular heartbeat (ie, atrial fibrillation) or a bundle branch block preventing electrical impulses from making your heart beat efficiently.
- Echocardiogram (ECHO): Uses sound waves captured through a hand-held wand that is placed on your chest to create two- and three-dimensional images of the heart. Echocardiogram findings help determine the speed and direction of blood flow in the heart. Findings associated with ATTR-CM include, but are not limited to, heart failure with preserved ejection fraction, also known as HFpEF, which relates to the amount of blood that passes through the heart with each beat.
- Cardiac magnetic resonance imaging (MRI): Uses radio waves, magnets and a computer to create detailed images of your heart. A Cardiac MRI is considered a painless, yet sensitive and specific diagnostic tool that helps identify transthyretin amyloidosis and light chain amyloidosis. However, it is currently unknown whether MRI has the capability to distinguish between amyloid types.